![]() Opuntia spp.: Characterization and Benefits in Chronic Diseases.ĭel Socorro Santos DÃaz, MarÃa Barba de la Rosa, Ana-Paulina Héliès-Toussaint, Cécile Guéraud, Françoise Nègre-Salvayre, Anne We conclude that Opuntia extracts are hepatoprotective and can be used as a nutraceutical to prevent ALF. ![]() Both extracts appeared to be superior to NAC when used therapeutically. In cultured hepatocytes, Opuntia extracts signiï¬cantly reduced leakage of LDH and cell necrosis, both prophylactically and therapeutically. The Opuntia extracts reversed APAP-induced depletion of liver GSH and glycogen stores. Both extracts signiï¬cantly attenuated APAP-induced injury markers AST, ALT and ALP and improved liver histology. Opuntia robusta had signiï¬cantly higher levels of antioxidants than Opuntia streptacantha. Rat hepatocyte cultures were exposed to 20mmol/LAPAP, and necrosis was assessed by LDH leakage. Fruit extracts (800mg/kg/day, orally were given prophylactically to male Wistar rats before intoxication with APAP (500 mg/kg, intraperitoneally. In addition, we analyzed the antioxidant activities of these extracts. The aim of this study was to evaluate the hepatoprotective effect of Opuntia robusta and Opuntia streptacantha extracts against APAP-induced ALF. fruits are an important source of nutrients and contain high levels of bioactive compounds, including antioxidants. N-acetyl-L-cysteine (NAC, the current therapy for APAP-induced ALF, is not always effective, and liver transplantation is often needed. Hepatoprotective Effect of Opuntia robusta and Opuntia streptacantha Fruits against Acetaminophen-Induced Acute Liver Damageĭirectory of Open Access Journals (Sweden)įull Text Available Acetaminophen (APAP-induced acute liver failure (ALF is a serious health problem in developed countries. Sixteen compounds were common to all the three Opuntia species. prolifera oil was composed of 46.6% alkanes and the primary hydrocarbon component was heptadecane (19.2%). ficus-indica with linoleic acid (22.3%), palmitic acid (12.7%), lauric acid (10.5%) and myristic acid (4.2%) as major fatty acids. ![]() Fatty acid-derived compounds dominated the essential oil of O. littoralis, with the two main components being the furanoid forms of cis-linalool oxide (10.8%) and trans-linalool oxide (8.8%). Terpenoids were the dominant class of volatiles in O. The essential oils from the cladodes of Opuntia littoralis, Opuntia ficus-indica and Opuntia prolifera growing wild on Santa Catalina Island, California, were obtained by hydrodistillation and analysed by gas chromatography-mass spectrometry (GC-MS). Chemical composition of volatiles from Opuntia littoralis, Opuntia ficus-indica, and Opuntia prolifera growing on Catalina Island, California.
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